Research

The Department of Infectious Diseases at the Medical College of Georgia at Augusta University conducts Clinical Trials relating to a wide variety of pertinent infectious diseases. The following is a non-comprehensive list of currently active studies in the department. If you are interested in learning more about a specific study, please contact the study coordinator listed for the study and we would be more than happy to provide you will further details.

ClinicalTrials.gov#	Official Title	Primary Investigator	Study Coordinator
ANCT04439071	Evaluation of the Efficacy and Safety of PTC299 in Hospitalized Subjects With COVID-19 (FITE19)	Jose Vazquez	Aprile Osborn
NCT04340388	Contribution of the Integrase Inhibitor Dolutegravir to Obesity and Cardiovascular Disease in Persons Living With HIV	Jonell Poe	Ryan Harris Amber Ladak Reva Crandall Jacob Looney
NCT04633187	A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Effects of EDP-938 in Adult Hematopoietic Cell Transplant Recipients With Acute Respiratory Syncytial Virus Infection of the Upper Respiratory Tract	Andrew Chao	Aprile Osborn
NCT04442737	A Phase 4, Randomized, Active-Controlled, Open-label Study to Evaluate the Safety and Tolerability of Switching to Once-Daily Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Fixed-dose Combination (FDC) Regimen in Virologically-suppressed Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Experiencing Rapid Weight Gain With an INI + TAF/FTC ARV Regimen	Cheryl Newman	Angela Stroman
NCT03059992	Open-Label Study to Evaluate the Efficacy and Safety of SCY-078 (Ibrexafungerp) in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment (FURI)	Jose Vazquez	Aprile Osborn
NCT04160468	A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Single Dose of Exebacase in Patients Receiving Standard-of-Care Antibiotics for the Treatment of Staphylococcus Aureus Bloodstream Infections (Bacteremia), Including Right-Sided Infective Endocarditis (DISRUPT)	Jose Vazquez	Aprile Osborn
NCT04650087	ACTIV-4C: A multicenter, adaptive, prospective, randomized trial evaluating the efficacy and safety of antithrombotic strategies in patients with COVID-19 following hospital discharge	Jose Vazquez	Ashton Bowles
NCT02735707	Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community-Acquired Pneumonia (REMAP-CAP)	Jose Vazquez	Ashton Bowles