Vaibhav Lab

Dr. Kumar Vaibhav is an Assistant Professor on tenure track in the Department of Neurosurgery at the Medical College of Georgia (MCG) at Augusta University, where he also holds an adjunct position in the Department of Oral Biology and Diagnostic Sciences.

He is also affiliated with Transdisciplinary Research Initiative in Inflammaging and Brain Aging (TRIBA) and The Graduate School at Augusta University. His academic journey has been marked by a strong foundation in toxicology, neuroanatomy, immunology and neuropharmacology, leading to a significant focus on neuroscience research, particularly in the areas of TBI, neurovascular injury, neuroimmunology, senescence, PTE, neurodegeneration and the effects of hypoxia and hypoglycemia on neuronal injury.

Jump to: Educational Background Professional Developments & Training Service & Student Success Research Focus & Contributions

Collaboration & Interdisciplinary Approach | Publications | Future Directions News

Educational Background

Dr. Vaibhav's educational background is diverse and multidisciplinary. He completed his Bachelor of Science in Chemistry from Vinoba Bhave University in India, followed by a Master of Science in Toxicology from Jamia Hamdard (Hamdard University), New Delhi. His early career involved practical experience in the pharmaceutical industry, where he worked on analytical development and bioequivalence studies. He earned his Ph.D. in Toxicology with a specialization in Stroke and Neuropharmacology from Jamia Hamdard, which laid the groundwork for his future research endeavors.

Following his doctoral studies, Dr. Vaibhav pursued two post-doctoral fellowships. The first was at the Dr. B R Ambedkar Center for Biomedical Research at the University of Delhi, focusing on the interplay between hypoxia-hypoglycemia and neuronal injury. The second fellowship at Augusta University emphasized neurovascular injury and neuroimmunology, areas that would define his research focus.

Professional Developments

Kumar Vaibhav's professional development activities focus on enhancing his skills as a leader, reviewer, moderator, speaker, and mentor. His goals are driven by commitments to research, leadership, education, institution, and mentorship. He has participated in various programs to improve team building, diversity, and leadership skills, including “SoftskillsTM Percipio” and the “Research Leadership course” by Robel Consulting LLC.

Vaibhav has given numerous invited talks, chaired symposiums, and completed workshops on molecular docking and simulation. He has reviewed and edited many manuscripts and grants, serving as an Associate Editor for several journals such as Frontiers in Neuroscience, Biomedicines etc. He has also been actively involved in institutional committees and professional societies, contributing to the scientific community and mentoring students.

He has received awards such as the AURI Emerging Scientist Award 2020 and the Outstanding Young Basic Science Faculty Award 2022, reflecting his significant contributions to professional development.

Teaching

Vaibhav has been actively involved in teaching at Augusta University (AU) since 2017, focusing on both research mentorship and direct teaching. As an Assistant Professor, his efforts include mentoring undergraduate and graduate students, medical scholars, research staff, and postdoctoral fellows. He delivers didactic lectures in the DCG graduate curriculum.

Vaibhav has expanded his teaching and mentorship at Augusta University (AU), focusing on research mentorship and direct teaching. He mentors undergraduate and graduate students, medical scholars, research staff, and postdoctoral fellows, using innovative instructional approaches to maximize engagement and success. His efforts are reflected in positive feedback and evaluations.

Since joining AU as an Assistant Professor in 2020, he has mentored numerous students, contributing to publications, presentations, and career progression. Vaibhav has also served on PhD Thesis Committees and received the 2022 Outstanding Young Basic Science Faculty Award. His commitment to diversity, inclusion, and leadership enhances his teaching and mentorship.

Service

Kumar Vaibhav's service statement highlights his commitment to advancing Augusta University's (AU) mission through faculty participation and knowledge dissemination in Neuroscience. He actively contributes to various institutional, national, and international committees. He has served on AU committees, reviewed award applications, and participated in admissions interviews. He is a dedicated member of the National Neurotrauma Society and other professional societies, contributing to mentorship and knowledge dissemination. Vaibhav is also involved in community service, particularly in judging school science fairs. His efforts exemplify his dedication to AU's vision and global student success.

Student Success

Vaibhav lab has been dedicated to inclusion of students in research and scientific work and to developing a research aptitude to fulfill their career goals since 2014. Our students have contributed to 23 publications, 8 talks in conferences (5 international, 1 national and 2 regional), and 17 posters (7 international, 4 national and 6 regional) and 4 individual awards in conferences within the last five years. Students and staffs who completed training in the lab, have been successful in their careers and currently working in the reputed institutions and medical school.

Our constant effort to adapt to our mentorship and teaching according to the individual’s need and background helped us to achieve this success. In summary, Vaibhav’s mentorship at institutional and national level represents a noteworthy contribution to the AU vision of education and has been instrumental to our students’ success and growth. For the effort as research faculty, Dr. Vaibhav has been awarded 2022 outstanding Young Basic Science Faculty Award by MCG.

Research Focus & Contributions

Dr. Vaibhav is the director of Brain Injury, Senescence, and Translational Neuroscience Lab in the Department of Neurosurgery. As an Assistant Professor in the Department of Neurosurgery, Kumar Vaibhav has secured continuous extramural funding since 2017, focusing on high-impact research in Neuroscience, particularly in Traumatic Brain Injury (TBI). His lab's pioneering work on cannabinoid receptors in brain macrophages has established him as a leader in this field.

Since his promotion in 2020, he has significantly advanced understanding of immune responses post-trauma. Despite COVID-19 challenges, his achievements include securing multiple grants, publishing 72 peer-reviewed articles (Over 4500 citations with h index 34 in Nov. 2024), delivering numerous invited talks, and chairing symposiums. He actively mentors students, contributing to their success in research. Vaibhav is committed to professional development and has received notable awards for his contributions to science.

Dr. Vaibhav's research is primarily centered on understanding the mechanisms underlying neurovascular injuries and the immune response in the nervous system. His work is particularly relevant to conditions such as stroke, traumatic brain injury, and neurodegenerative diseases, where both neuronal damage and inflammatory responses play critical roles. . His work is characterized by a rigorous experimental approach, often involving in vitro and in vivo models to study neurovascular and neuroimmune interactions. His research findings have implications for developing new therapeutic strategies to treat various neurological disorders. By identifying the molecular targets involved in neurovascular injuries and the immune response, Dr. Vaibhav's work paves the way for potential interventions that could enhance recovery and improve patient outcomes.

Neurovascular Injury:

Dr. Vaibhav investigates the cellular and molecular mechanisms that contribute to neurovascular injury after TBI and hemorrhages. This includes studying the Neuroinflammation, blood-brain barrier's integrity and how it is compromised during pathological conditions. His research aims to identify potential therapeutic targets that could mitigate or prevent injury, thereby improving outcomes for patients suffering from cerebrovascular disorders.

TBI & Neurodegeneration:

One of the focus area of research in the lab is to explore chronic pathology post-TBI and TBI-associated neurodegeneration. The lab is actively exploring the cerebral atrophy, behavioral deficits and immunosenescence in chronic period.

Neuroimmunology:

Another significant aspect of Dr. Vaibhav's research is neuroimmunology, which examines the interactions between the nervous system and the immune system. He explores how immune responses can exacerbate or ameliorate neuronal injury. By understanding these interactions, Dr. Vaibhav aims to develop strategies that could harness the immune system to promote neuronal repair and recovery following injury.

Hypoxia & Hypoglycemia:

His earlier studies on hypoxia and hypoglycemia have provided insights into how these conditions lead to neuronal injury. Dr. Vaibhav's research has shown that the brain's response to low oxygen and glucose levels can trigger a cascade of neurodegenerative processes. By elucidating these pathways, he seeks to identify novel neuroprotective strategies that could be employed in clinical settings.

Stroke & Neuropharmacology:

Dr. Vaibhav's Ph.D. work focused on stroke and neuropharmacology, where he investigated the pharmacological agents that could potentially protect neurons from ischemic damage. His findings contribute to the broader understanding of how certain drugs can modulate neuroinflammation and promote neuronal survival during and after a stroke.

Collaboration & Interdisciplinary Approach

Dr. Vaibhav is known for his collaborative spirit, often working with colleagues from various disciplines, including neurology, immunology, biochemistry, vascular biology, neuroscience, radiology and pharmacology. This interdisciplinary approach enriches his research and fosters innovation, allowing for a more comprehensive understanding of complex neurological conditions.

Publications

Google Scholar

Publication
Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach 2.0 Ahluwalia, P., Gaur, P., Ahluwalia, M. & Vaibhav, K., Nov 2024, In: Biomedicines. 12, 11, 2586. Research output: Contribution to journal › Editorial › peer-review
Boosting Acetylcholine Signaling by Cannabidiol in a Murine Model of Alzheimer’s Disease Khodadadi, H., Salles, É. L., Naeini, S. E., Bhandari, B., Rogers, H. M., Gouron, J., Meeks, W., Terry, A. V., Pillai, A., Yu, J. C., Morgan, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M., Wang, L. P. & Baban, B., Nov 2024, In: International journal of molecular sciences. 25, 21, 11764. Research output: Contribution to journal › Article › peer-review
Single episode of moderate to severe traumatic brain injury leads to chronic neurological deficits and Alzheimer’s-like pathological dementia Vaibhav, K., Gulhane, M., Ahluwalia, P., Kumar, M., Ahluwalia, M., Rafiq, A. M., Amble, V., Zabala, M. G., Miller, J. B., Goldman, L., Mondal, A. K., Deak, F., Kolhe, R., Arbab, A. S. & Vale, F. L., Dec 2024, In: GeroScience. 46, 6, p. 5439-5457 19 p. Research output: Contribution to journal › Article › peer-review
Altering biomolecular condensates as a potential mechanism that mediates cannabidiol effect on glioblastoma Wang, L. P., Chagas, P. S., Salles, É. L., Naeini, S. E., Gouron, J., Rogers, H. M., Khodadadi, H., Bhandari, B., Alptekin, A., Qin, X., Vaibhav, K., Costigliola, V., Hess, D. C., Dhandapani, K. M., Arbab, A. S., Rutkowski, M., Yu, J. C. & Baban, B., Jun 2024, In: Medical Oncology. 41, 6, 140. Research output: Contribution to journal › Article › peer-review
Design and Development of E-axle as a Retro and OE Fitment Solution for Light Commercial Vehicles Ranging from 1.5 to 5 Ton GVW Vaibhav, K., Mulik, R. V. & Shrikrishna Ramdasi, S., Jan 16 2024, In: SAE Technical Papers. Research output: Contribution to journal › Conference article › peer-review
Incorporating Novel Technologies in Precision Oncology for Colorectal Cancer: Advancing Personalized Medicine Ahluwalia, P., Ballur, K., Leeman, T., Vashisht, A., Singh, H., Omar, N., Mondal, A. K., Vaibhav, K., Baban, B. & Kolhe, R., Feb 2024, In: Cancers. 16, 3, 480. Research output: Contribution to journal › Review article › peer-review
A Machine Learning Approach for Moderating Toxic Hinglish Comments of YouTube Videos Singh, A., Vaibhav, K. & Arora, M., 2024, Data Science and Applications - Proceedings of ICDSA 2023. Nanda, S. J., Yadav, R. P., Gandomi, A. H. & Saraswat, M. (eds.). Springer Science and Business Media Deutschland GmbH, p. 173-187 15 p. (Lecture Notes in Networks and Systems; vol. 820). Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Inhalant Cannabidiol Inhibits Glioblastoma Progression Through Regulation of Tumor Microenvironment Khodadadi, H., Salles, É. L., Alptekin, A., Mehrabian, D., Rutkowski, M., Arbab, A. S., Yeudall, W. A., Yu, J. C., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Baban, B., Oct 1 2023, In: Cannabis and Cannabinoid Research. 8, 5, p. 824-834 11 p. Research output: Contribution to journal › Article › peer-review
Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach Ahluwalia, M., Gaur, P. & Vaibhav, K., Jul 2023, In: Biomedicines. 11, 7, 1947. Research output: Contribution to journal › Editorial › peer-review
Recombinant human DNase-I improves acute respiratory distress syndrome via neutrophil extracellular trap degradation Jarrahi, A., Khodadadi, H., Moore, N. S., Lu, Y., Awad, M. E., Salles, E. L., Vaibhav, K., Baban, B. & Dhandapani, K. M., Sep 2023, In: Journal of Thrombosis and Haemostasis. 21, 9, p. 2473-2484 12 p. Research output: Contribution to journal › Article › peer-review
Honey: A Sweet Way to Health Ahluwalia, M., Ahluwalia, P., Dhandapani, K. M. & Vaibhav, K., Jan 1 2020, Therapeutic Applications of Honey and its Phytochemicals: Vol.1. Springer Singapore, Vol. 1. p. 53-80 28 p. Research output: Chapter in Book/Report/Conference proceeding › Chapter
A potential role for cannabichromene in modulating TRP channels during acute respiratory distress syndrome Khodadadi, H., Salles, É. L., Shin, E., Jarrahi, A., Costigliola, V., Kumar, P., Yu, J. C., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Baban, B., Dec 2021, In: Journal of Cannabis Research. 3, 1, 45. Research output: Contribution to journal › Article › peer-review
Altered endocannabinoid metabolism compromises the brain-CSF barrier and exacerbates chronic deficits after traumatic brain injury in mice Ahluwalia, M., Mcmichael, H., Kumar, M., Espinosa, M. P., Bosomtwi, A., Lu, Y., Khodadadi, H., Jarrahi, A., Khan, M. B., Hess, D. C., Rahimi, S. Y., Vender, J. R., Vale, F. L., Braun, M., Baban, B., Dhandapani, K. M. & Vaibhav, K., Mar 2023, In: Experimental Neurology. 361, 114320. Research output: Contribution to journal › Article › peer-review
Understanding Acquired Brain Injury: A Review Goldman, L., Siddiqui, E. M., Khan, A., Jahan, S., Rehman, M. U., Mehan, S., Sharma, R., Budkin, S., Kumar, S. N., Sahu, A., Kumar, M. & Vaibhav, K., Sep 2022, In: Biomedicines. 10, 9, 2167. Research output: Contribution to journal › Review article › peer-review
Herbal drugs an alternative medicine for the treatment of neurodegenerative diseases: Preclinical and clinical trial review Shrivastava, P., Revoori, A., Vaibhav, K., Ahluwalia, M. & Saxena, M., Jan 1 2022, Herbal Medicines: A Boon for Healthy Human Life. Elsevier, p. 3-17 15 p. Research output: Chapter in Book/Report/Conference proceeding › Chapter
Pilot Study of Remote Ischemic Conditioning in Acute Spontaneous Intracerebral Hemorrhage Jarrahi, A., Shah, M., Ahluwalia, M., Khodadadi, H., Vaibhav, K., Bruno, A., Baban, B., Hess, D. C., Dhandapani, K. M. & Vender, J. R., May 12 2022, In: Frontiers in Neuroscience. 16, 791035. Research output: Contribution to journal › Article › peer-review
Nigella sativa and its active principles: Potential food for healthy living Bhatt, D. N., Ansari, S., Fonseca, W. F., Vaibhav, K. & Ahluwalia, M., Jan 1 2021, Black Seeds (Nigella sativa): Pharmacological and Therapeutic Applications. Elsevier, p. 197-216 20 p. Research output: Chapter in Book/Report/Conference proceeding › Chapter
Black seed (Nigella sativa): Pharmacological and therapeutic applications in endocrine dysfunction Fonseca, W. F., Ahluwalia, P., Bhatt, D. N., Ansari, S., Tabassum, R., Vaibhav, K. & Ahluwalia, M., Jan 1 2021, Black Seeds (Nigella sativa): Pharmacological and Therapeutic Applications. Elsevier, p. 405-422 18 p. Research output: Chapter in Book/Report/Conference proceeding › Chapter
Inflammaging and Cannabinoids Baban, B., Khodadadi, H., Salles, É. L., Costigliola, V., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Yu, J. C., Dec 2021, In: Ageing Research Reviews. 72, p. 101487 101487. Research output: Contribution to journal › Article › peer-review
Rescuing mitochondria in traumatic brain injury and intracerebral hemorrhages - A potential therapeutic approach Ahluwalia, M., Kumar, M., Ahluwalia, P., Rahimi, S., Vender, J. R., Raju, R. P., Hess, D. C., Baban, B., Vale, F. L., Dhandapani, K. M. & Vaibhav, K., Nov 2021, In: Neurochemistry International. 150, 105192. Research output: Contribution to journal › Article › peer-review
Conditioning medicine for ischemic and hemorrhagic stroke Hess, D. C., Khan, M. B., Kamat, P., Vaibhav, K., Dhandapani, K. M., Baban, B., Waller, J. L., Hoda, M. N., Blauenfeldt, R. A. & Andersen, G., Jun 2021, In: Conditioning medicine. 4, 3, p. 124-129 6 p. Research output: Contribution to journal › Article › peer-review
Pharmacological and therapeutic approaches in the treatment of epilepsy Ghosh, S., Sinha, J. K., Khan, T., Devaraju, K. S., Singh, P., Vaibhav, K. & Gaur, P., May 2021, In: Biomedicines. 9, 5, 470. Research output: Contribution to journal › Review article › peer-review
Infection and Immune Memory: Variables in Robust Protection by Vaccines Against SARS-CoV-2 Ahluwalia, P., Vaibhav, K., Ahluwalia, M., Mondal, A. K., Sahajpal, N., Rojiani, A. M. & Kolhe, R., May 2021, In: Frontiers in immunology. 12, p. 660019 660019. Research output: Contribution to journal › Review article › peer-review
Cannabidiol ameliorates cognitive function via regulation of IL-33 and TREM2 upregulation in a murine model of Alzheimer's Disease Khodadadi, H., Salles, É. L., Jarrahi, A., Costigliola, V., Khan, M. B., Yu, J. C., Morgan, J. C., Hess, D. C., Vaibhav, K., Dhandapani, K. M. & Baban, B., 2021, In: Journal of Alzheimer's Disease. 80, 3, p. 973-977 5 p. Research output: Contribution to journal › Article › peer-review
AMPK induces regulatory innate lymphoid cells after traumatic brain injury Baban, B., Braun, M., Khodadadi, H., Ward, A., Alverson, K., Malik, A., Nguyen, K., Nazarian, S., Hess, D. C., Forseen, S., Post, A. F., Vale, F. L., Vender, J. R., Nasrul Hoda, M., Akbari, O., Vaibhav, K. & Dhandapani, K. M., Jan 11 2021, In: JCI Insight. 6, 1, e126766. Research output: Contribution to journal › Article › peer-review
Occupational exposure to pesticides in female tea garden workers and adverse birth outcomes Kumar, S. N., Vaibhav, K., Bastia, B., Singh, V., Ahluwalia, M., Agrawal, U., Borgohain, D., Raisuddin, S. & Jain, A. K., Mar 2021, In: Journal of Biochemical and Molecular Toxicology. 35, 3, e22677. Research output: Contribution to journal › Article › peer-review
Infections of the lung: a predictive, preventive and personalized perspective through the lens of evolution, the emergence of SARS-CoV-2 and its pathogenesis Ahluwalia, P., Ahluwalia, M., Vaibhav, K., Mondal, A., Sahajpal, N., Islam, S., Fulzele, S., Kota, V., Dhandapani, K., Baban, B., Rojiani, A. M. & Kolhe, R., Dec 2020, In: EPMA Journal. 11, 4, p. 581-601 21 p. Research output: Contribution to journal › Review article › peer-review
Revisiting traumatic brain injury: From molecular mechanisms to therapeutic interventions Jarrahi, A., Braun, M., Ahluwalia, M., Gupta, R. V., Wilson, M., Munie, S., Ahluwalia, P., Vender, J. R., Vale, F. L., Dhandapani, K. M. & Vaibhav, K., Oct 2020, In: Biomedicines. 8, 10, p. 1-42 42 p., 389. Research output: Contribution to journal › Review article › peer-review
Neurological consequences of COVID-19: What have we learned and where do we go from here? Jarrahi, A., Ahluwalia, M., Khodadadi, H., Da Silva Lopes Salles, E., Kolhe, R., Hess, D. C., Vale, F., Kumar, M., Baban, B., Vaibhav, K. & Dhandapani, K. M., Sep 30 2020, In: Journal of Neuroinflammation. 17, 1, 286. Research output: Contribution to journal › Review article › peer-review
Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA Khodadadi, H., Salles, É. L., Jarrahi, A., Chibane, F., Costigliola, V., Yu, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M. & Baban, B., Sep 1 2020, In: Cannabis and Cannabinoid Research. 5, 3, p. 197-201 5 p. Research output: Contribution to journal › Article › peer-review
Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury Vaibhav, K., Braun, M., Alverson, K., Khodadadi, H., Kutiyanawalla, A., Ward, A., Banerjee, C., Sparks, T., Malik, A., Rashid, M. H., Rashid, M. H., Khan, M. B., Waters, M. F., Hess, D. C., Arbab, A. S., Vender, J. R., Hoda, N., Hoda, N., Hoda, N. & Baban, B. & 1 others, Dhandapani, K. M., May 2020, In: Science Advances. 6, 22, p. eaax8847 EAAX8847. Research output: Contribution to journal › Article › peer-review
Targeting the endocannabinoid system: a predictive, preventive, and personalized medicine-directed approach to the management of brain pathologies Reddy, V., Grogan, D., Ahluwalia, M., Salles, É. L., Ahluwalia, P., Khodadadi, H., Alverson, K., Nguyen, A., Raju, S. P., Gaur, P., Braun, M., Vale, F. L., Costigliola, V., Dhandapani, K., Baban, B. & Vaibhav, K., Jun 1 2020, In: EPMA Journal. 11, 2, p. 217-250 34 p. Research output: Contribution to journal › Review article › peer-review
Bone Marrow Derived Extracellular Vesicles Activate Osteoclast Differentiation in Traumatic Brain Injury Induced Bone Loss Singleton, Q., Vaibhav, K., Braun, M., Patel, C., Khayrullin, A., Mendhe, B., Lee, B. R., Kolhe, R., Kaiser, H., Awad, M. E., Fariyike, T., Elsayed, R., Elsalanty, M. E., Isales, C. M., Liu, Y., Hamrick, M. W., Dhandapani, K. M. & Fulzele, S., Jan 2021, In: Fuel Cells. 8, 1, 63. Research output: Contribution to journal › Article › peer-review
Regulation of Innate Lymphoid Cells in Acute Kidney Injury: Crosstalk between Cannabidiol and GILZ Baban, B., Khodadadi, H., Vaibhav, K., Marchetti, C., Riccardi, C. & Mozaffari, M. S., 2020, In: Journal of Immunology Research. 2020, p. 6056373 6056373. Research output: Contribution to journal › Article › peer-review
Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation Vaibhav, K., Braun, M., Khan, M. B., Fatima, S., Saad, N., Shankar, A., Khan, Z. T., Harris, R. B. S., Yang, Q., Huo, Y., Arbab, A. S., Giri, S., Alleyne, C. H., Vender, J. R., Hess, D. C., Baban, B., Hoda, M. N. & Dhandapani, K. M., Oct 1 2018, In: Journal of Experimental Medicine. 215, 10, p. 2636-2654 19 p. Research output: Contribution to journal › Article › peer-review
Impact of cannabidiol treatment on regulatory T-17 cells and neutrophil polarization in acute kidney injury Baban, B., Hoda, N., Malik, A., Khodadadi, H., Simmerman, E., Vaibhav, K. & Mozaffari, M. S., Oct 5 2018, In: American Journal of Physiology - Renal Physiology. 315, 4, p. F1149-F1158 Research output: Contribution to journal › Article › peer-review
Delayed administration of zingerone mitigates the behavioral and histological alteration via repression of oxidative stress and intrinsic programmed cell death in focal transient ischemic rats Vaibhav, K., Shrivastava, P., Tabassum, R., Khan, A., Javed, H., Ahmed, M. E., Islam, F., Safhi, M. M. & Islam, F., Nov 12 2013, In: Pharmacology Biochemistry and Behavior. 113, p. 53-62 10 p. Research output: Contribution to journal › Article › peer-review
1,8-Cineole (eucalyptol) mitigates inflammation in amyloid beta toxicated PC12 cells: Relevance to alzheimer's disease Islam, F., Khan, A., Vaibhav, K., Javed, H., Tabassum, R., Ahmed, M. E., Khan, M. M., Khan, M. B., Shrivastava, P., Islam, F., Siddiqui, M. S. & Safhi, M. M., Feb 2014, In: Neurochemical Research. 39, 2, p. 344-352 9 p. Research output: Contribution to journal › Article › peer-review
Improved cisplatin delivery in cervical cancer cells by utilizing folate-grafted non-aggregated gelatin nanoparticles Dixit, N., Vaibhav, K., Pandey, R. S., Jain, U. K., Katare, O. P., Katyal, A. & Madan, J., Feb 1 2015, In: Biomedicine and Pharmacotherapy. 69, p. 1-10 10 p. Research output: Contribution to journal › Article › peer-review
Attenuation of oxidative damage-associated cognitive decline by Withania somnifera in rat model of streptozotocin-induced cognitive impairment Ahmed, M. E., Javed, H., Khan, M. M., Vaibhav, K., Ahmad, A., Khan, A., Tabassum, R., Islam, F., Safhi, M. M. & Islam, F., Oct 2013, In: Protoplasma. 250, 5, p. 1067-1078 12 p. Research output: Contribution to journal › Article › peer-review
Taurine ameliorates neurobehavioral, neurochemical and immunohistochemical changes in sporadic dementia of Alzheimer's type (SDAT) caused by intracerebroventricular streptozotocin in rats Islam, F., Javed, H., Khan, A., Vaibhav, K., Moshahid Khan, M., Ahmad, A., Ejaz Ahmad, M., Ahmad, A., Tabassum, R., Islam, F. & Safhi, M. M., Dec 1 2013, In: Neurological Sciences. 34, 12, p. 2181-2192 12 p. Research output: Contribution to journal › Article › peer-review
Terminalia arjuna bark extract inhibits histological alterations by mitigating oxidative stress in lead intoxicated mice Mohammed Raouf, G. A., Vaibhav, K., Khan, A., Tabassum, R., Ahmed, M. E., Javed, H., Chander, K., Islam, F. & Siddiqui, M. S., Dec 2013, In: Oriental Pharmacy and Experimental Medicine. 13, 4, p. 253-265 13 p. Research output: Contribution to journal › Article › peer-review
Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress Islam, F., Khan, A., Vaibhav, K., Javed, H., Moshahid Khan, M., Tabassum, R., Ahmed, M. E., Srivastava, P., Khuwaja, G., Islam, F., Saeed Siddiqui, M. & Shafi, M. M., Oct 2012, In: Molecular and Cellular Biochemistry. 369, 1-2, p. 55-65 11 p. Research output: Contribution to journal › Article › peer-review
Naringenin ameliorates Alzheimer's disease (AD)-type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular- streptozotocin in rat model Khan, M. B., Khan, M. M., Khan, A., Ahmed, M. E., Ishrat, T., Tabassum, R., Vaibhav, K., Ahmad, A. & Islam, F., Dec 2012, In: Neurochemistry International. 61, 7, p. 1081-1093 13 p. Research output: Contribution to journal › Article › peer-review
Quercetin mitigates lead acetate-induced behavioral and histological alterations via suppression of oxidative stress, Hsp-70, Bak and upregulation of Bcl-2 Chander, K., Vaibhav, K., Ejaz Ahmed, M., Javed, H., Tabassum, R., Khan, A., Kumar, M., Katyal, A., Islam, F. & Saeed Siddiqui, M., Jun 2014, In: Food and Chemical Toxicology. 68, p. 297-306 10 p. Research output: Contribution to journal › Article › peer-review
Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: Behavioral, neurochemical and immunohistochemical studies Khuwaja, G., Khan, M. M., Ishrat, T., Ahmad, A., Raza, S. S., Ashafaq, M., Javed, H., Khan, M. B., Khan, A., Vaibhav, K., Safhi, M. M. & Islam, F., Jan 12 2011, In: Brain Research. 1368, p. 254-263 10 p. Research output: Contribution to journal › Article › peer-review
Perillyl alcohol improves functional and histological outcomes against ischemia-reperfusion injury by attenuation of oxidative stress and repression of COX-2, NOS-2 and NF-κB in middle cerebral artery occlusion rats Islam, F., Tabassum, R., Vaibhav, K., Shrivastava, P., Khan, A., Ahmed, M. E., Ashafaq, M., Khan, M. B., Islam, F. & Safhi, M. M., Jan 15 2015, In: European Journal of Pharmacology. 747, p. 190-199 10 p. Research output: Contribution to journal › Article › peer-review
Piperine suppresses cerebral ischemia-reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat model Vaibhav, K., Shrivastava, P., Javed, H., Khan, A., Ahmed, M. E., Tabassum, R., Khan, M. M., Khuwaja, G., Islam, F., Saeed Siddiqui, M., Safhi, M. M. & Islam, F., Aug 2012, In: Molecular and Cellular Biochemistry. 367, 1-2, p. 73-84 12 p. Research output: Contribution to journal › Article › peer-review
Bacopa monniera ameliorates cognitive impairment and neurodegeneration induced by intracerebroventricular-streptozotocin in rat: behavioral, biochemical, immunohistochemical and histopathological evidences Khan, M. B., Ahmad, M., Ahmad, S., Ishrat, T., Vaibhav, K., Khuwaja, G. & Islam, F., Feb 2014, In: Metabolic Brain Disease. 30, 1, p. 115-127 13 p. Research output: Contribution to journal › Article › peer-review
Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type Javed, H., Khan, M. M., Ahmad, A., Vaibhav, K., Ahmad, M. E., Khan, A., Ashafaq, M., Islam, F., Siddiqui, M. S., Safhi, M. M. & Islam, F., May 17 2012, In: Neuroscience. 210, p. 340-352 13 p. Research output: Contribution to journal › Article › peer-review

Future Directions

Looking forward, Dr. Vaibhav aims to expand his research into the role of other organs in neuroinflammatory processes and neurovascular health. His lab has expanded the work in TBI-induced senescence and neurodegeneration. He is also interested in exploring the potential of regenerative medicine and stem cell therapies in promoting recovery from neurovascular injuries.

In addition to his research, Dr. Vaibhav is dedicated to teaching and mentoring students and trainees in the field of neuroscience. He believes in fostering the next generation of scientists and clinicians who will continue to advance our understanding of the nervous system and its disorders.

Dr. Kumar Vaibhav's research at Augusta University represents a significant contribution to the field of neuroscience. His work not only enhances our understanding of the underlying mechanisms of neurological disorders but also holds promise for developing new therapeutic strategies that could ultimately improve patient care. As he continues to explore these critical areas of research, Dr. Vaibhav remains committed to advancing the field of neuroscience and training future scientists.

Lab Staffs

Mayuri Gulhane

Mayuri Gulhane is a Research Associate in the Department of Neurosurgery, currently focused on “Traumatic Brain Injury (TBI)”, TBI-induced retinopathy, Histology, Flow Cytometry, PCRs, Cell culture and other laboratorial work. With a strong academic background in Veterinary Science (BVSc) and a Master's degree (MVSC) in Animal Biotechnology, she brings a unique interdisciplinary approach to her research. Her work aims to deepen the understanding of neuropathological conditions resulting from brain injuries, contributing to innovative treatments and enhanced recovery.

Tabitha Royal

Tabitha Royal is a research associate in Vaibhav's Lab at MCG-Neurosurgery, Augusta University, where she has been a member of the lab staff since April 2024. She earned her Bachelor's degree in Pharmacy (B. Pharm) from the Birla Institute of Technology and Science, Pilani, in 2021, followed by a Master's degree in Neuroscience (MSc.) from Tel Aviv University in 2023. Tabitha specializes in molecular biology techniques and histology, assists with the maintenance of the mouse colony, and is skilled in mouse handling and the induction of Traumatic Brain Injury through controlled cortical impact, contributing to the lab’s research efforts.

Medical Students

Mario Espinosa

Liam Goldman

(Doing Residency in UT, Austin)

Undergraduate Students

Manuela Guzman Zabala

She is a Junior year student and a first graduate in the family, exploring circulatory defects post-TBI

Tajman Randhawa

He is also a Junior student and exploring the sexual dimorphism in brain injury.

Sriram Budim

He is a sophomore student and working on neurodegeneration.

Vibha Amble