Phone: (706) 721-8819
Fax: (706) 721-7299
Email: zbagi@augusta.edu
Office: CA-3133
Lab: CA-3132A
General Semmelweis University of Budap, Biomedical Sciences, PhD, 2004
Semmelweis University of Budap, Medicine, MD, 2000
2001-2010| Assistant Professor, New York Medical College
2010-2012 | Intermediate Research Fellow, British Heart Foundation Center of Research Excellence at University of Oxford
2011-2013 | Senior Research Fellow, Somerville College, Oxford University
2013 - 2019 | Associate Professor, Augusta University
2019 | Professor, Deparment of Physiology, Medical College of Georgia, Augusta University
Jump to: Research Interests Awards & Honors Related Links About Dr. Bagi's Research Lab
LAB PERSONNEL
Liwei Lang, PhD
Assistant Research Scientist
Marta Bagine Balogh
Research Associate
Vadym Buncha
Graduate Student
Katherine Fopiano
Graduate Student
Coronary microvascular disease in patients with diabetes mellitus and diastolic heart failure.
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Endothelial cell-selective adhesion molecule deficiency exhibits increased pulmonary vascular resistance due to impaired endothelial nitric oxide signalingBuncha, V., Lang, L., Fopiano, K. A., Ilatovskaya, D. V., Kapuku, G., Verin, A. D. & Bagi, Z., Feb 2025, In: American Journal of Physiology - Heart and Circulatory Physiology. 328, 2, p. H283-H293Research output: Contribution to journal › Article › peer-review |
PDE9A Inhibition Improves Coronary Microvascular Rarefaction and Left Ventricular Diastolic Dysfunction in the ZSF1 Rat Model of HFpEFFopiano, K. A., Zhazykbayeva, S., El-Battrawy, I., Buncha, V., Pearson, W. M., Hardell, D. J., Lang, L., Hamdani, N. & Bagi, Z., Nov 2024, In: Microcirculation. 31, 8, e12888.Research output: Contribution to journal › Article › peer-review |
Altered copper transport in oxidative stress-dependent brain endothelial barrier dysfunction associated with Alzheimer's diseaseHossain, M. S., Das, A., Rafiq, A. M., Deák, F., Bagi, Z., Outlaw, R., Sudhahar, V., Yamamoto, M., Kaplan, J. H., Ushio-Fukai, M. & Fukai, T., Dec 2024, In: Vascular Pharmacology. 157, 107433.Research output: Contribution to journal › Article › peer-review |
Phosphodiesterase 9A inhibition improves aging-related increase in pulmonary vascular resistance in miceBuncha, V., Fopiano, K. A., Lang, L., Ilatovskaya, D. V., Verin, A. & Bagi, Z., Oct 2024, In: GeroScience. 46, 5, p. 5191-5202 12 p.Research output: Contribution to journal › Article › peer-review |
AGPAT3 deficiency impairs adipocyte differentiation and leads to a lean phenotype in miceZhou, H., Fick, K., Patel, V., Hilton, L. R., Kim, H. W., Bagi, Z., Weintraub, N. L. & Chen, W., Jul 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 327, 1, p. E69-E80Research output: Contribution to journal › Article › peer-review |
Zinc-Dependent Histone Deacetylases in Lung Endothelial PathobiologyPatil, R. S., Maloney, M. E., Lucas, R., Fulton, D. J. R., Patel, V., Bagi, Z., Kovacs-Kasa, A., Kovacs, L., Su, Y. & Verin, A. D., Feb 2024, In: Biomolecules. 14, 2, 140.Research output: Contribution to journal › Review article › peer-review |
The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer’s diseaseTian, Y., Fopiano, K. A., Buncha, V., Lang, L., Suggs, H. A., Wang, R., Rudic, R. D., Filosa, J. A. & Bagi, Z., 2023, In: Frontiers in Molecular Neuroscience. 16, 1125932.Research output: Contribution to journal › Article › peer-review |
Microvascular contributions to white matter injury in Alzheimer’s diseaseBagi, Z., Sherman, L. S. & Back, S. A., 2023, In: Aging. 15, 16, p. 7860-7862 3 p.Research output: Contribution to journal › Editorial › peer-review |
Mice with endothelial cell-selective adhesion molecule deficiency develop coronary microvascular rarefaction and left ventricle diastolic dysfunctionBuncha, V., Fopiano, K. A., Lang, L., Williams, C., Horuzsko, A., Filosa, J. A., Kapuku, G. & Bagi, Z., Mar 2023, In: Physiological reports. 11, 6, e15643.Research output: Contribution to journal › Article › peer-review |
Multispectral LEDs Eliminate Lipofuscin-Associated Autofluorescence for Immunohistochemistry and CD44 Variant Detection by in Situ Hybridization in Aging Human, non-Human Primate, and Murine BrainAdeniyi, P. A., Fopiano, K. A., Banine, F., Garcia, M., Gong, X., Keene, C. D., Sherman, L. S., Bagi, Z. & Back, S. A., 2022, In: ASN Neuro. 14Research output: Contribution to journal › Article › peer-review |
Deficiency of Myeloid Pfkfb3 Protects Mice From Lung Edema and Cardiac Dysfunction in LPS-Induced EndotoxemiaXu, J., Wang, L., Yang, Q., Ma, Q., Zhou, Y., Cai, Y., Mao, X., Da, Q., Lu, T., Su, Y., Bagi, Z., Lucas, R., Liu, Z., Hong, M., Ouyang, K. & Jiao, K., 2021, In: Frontiers in Cardiovascular Medicine. 8, p. 745810 745810.Research output: Contribution to journal › Article › peer-review |
Association of cerebral microvascular dysfunction and white matter injury in Alzheimer’s diseaseBagi, Z., Kroenke, C. D., Fopiano, K. A., Tian, Y., Filosa, J. A., Sherman, L. S., Larson, E. B., Keene, C. D., Degener O’Brien, K., Adeniyi, P. A. & Back, S. A., Aug 2022, In: GeroScience. 44, 4, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review |
Coronary Microvascular Dysfunction and Heart Failure with Preserved Ejection Fraction-implications for Chronic Inflammatory MechanismsFopiano, K. A., Jalnapurkar, S., Davila, A. C., Arora, V. & Bagi, Z., Mar 2022, In: Current Cardiology Reviews. 18, 2, p. 6-14 9 p., e310821195986.Research output: Contribution to journal › Article › peer-review |
Role of Caveolae in the Development of Microvascular Dysfunction and Hyperglycemia in Type 2 DiabetesTian, Y., Fopiano, K. A., Patel, V. S., Feher, A. & Bagi, Z., Feb 18 2022, In: Frontiers in Physiology. 13, 825018.Research output: Contribution to journal › Article › peer-review |
GDP in Dialysis Associates with Peritoneal Vascular Remodeling in Kidney DiseaseHan, Q., Orr, Z. J., DeSouza, G. K., Bagi, Z. & Rudic, R. D., Aug 20 2021, In: Circulation research. 129, 5, p. 527-529 3 p.Research output: Contribution to journal › Review article › peer-review |
Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17Tian, Y., Fopiano, K. A., Buncha, V., Lang, L., Rudic, R. D., Filosa, J. A., Dou, H. & Bagi, Z., Feb 2022, In: GeroScience. 44, 1, p. 349-369 21 p.Research output: Contribution to journal › Article › peer-review |
Review: Circadian clocks and rhythms in the vascular treeHan, Q., Bagi, Z. & Daniel Rudic, R., Aug 2021, In: Current Opinion in Pharmacology. 59, p. 52-60 9 p.Research output: Contribution to journal › Review article › peer-review |
Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidationKolijn, D., Pabel, S., Tian, Y., Lódi, M., Herwig, M., Carrizzo, A., Zhazykbayeva, S., Kovács, Á., Fülöp, G., Falcão-Pires, I., Reusch, P. H., Linthout, S. V., Papp, Z., Van Heerebeek, L., Vecchione, C., Maier, L. S., Ciccarelli, M., Tschöpe, C., Mügge, A. & Bagi, Z. & 2 others, , Feb 1 2021, In: Cardiovascular Research. 117, 2, p. 495-507 13 p.Research output: Contribution to journal › Article › peer-review |
A Novel Subset of CD95+ Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy ObesityJohnson, C., Drummer IV, C., Shan, H., Shao, Y., Sun, Y., Lu, Y., Saaoud, F., Xu, K., Nanayakkara, G., Fang, P., Bagi, Z., Jiang, X., Choi, E. T., Wang, H. & Yang, X., Jan 7 2021, In: Frontiers in immunology. 11, 619951.Research output: Contribution to journal › Article › peer-review |
Effects of race, cardiac mass, and cardiac load on myocardial function trajectories from childhood to young adulthood: The augusta heart studyKapuku, G., Howie, M., Ghosh, S., Doshi, V., Bykhovsky, M., Ange, B., Halbert, J. D., Robinson, V., Bagi, Z., Harshfield, G. & George, V., 2021, In: Journal of the American Heart Association. 10, 3, p. 1-8 8 p., e015612.Research output: Contribution to journal › Article › peer-review |
Rapid decline of resting heart rate trajectories from childhood to young adulthood is paradoxically associated with increased cardiac massHao, G., Halbert, J., Su, S., Bagi, Z., Robinson, V., Thayer, J., Harshfield, G. & Kapuku, G., 2021, In: Acta Cardiologica. 76, 10, p. 1117-1123 7 p.Research output: Contribution to journal › Article › peer-review |
Prkaa1 Metabolically Regulates Monocyte/Macrophage Recruitment and Viability in Diet-Induced Murine Metabolic DisordersYang, Q., Ma, Q., Xu, J., Liu, Z., Zou, J., Shen, J., Zhou, Y., Da, Q., Mao, X., Lu, S., Fulton, D. J., Weintraub, N. L., Bagi, Z., Hong, M. & Huo, Y., 2020, In: Frontiers in Cell and Developmental Biology. 8, p. 611354 611354.Research output: Contribution to journal › Article › peer-review |
Vasculo-Neuronal Coupling and Neurovascular Coupling at the Neurovascular Unit: Impact of HypertensionPresa, J. L., Saravia, F., Bagi, Z. & Filosa, J. A., Sep 25 2020, In: Frontiers in Physiology. 11, 584135.Research output: Contribution to journal › Review article › peer-review |
Adenosine kinase inhibition enhances microvascular dilator function and improves left ventricle diastolic dysfunctionDavila, A., Tian, Y., Czikora, I., S. Weissman, A., Weinand, N., Dong, G., Xu, J., Li, J., Su, H., Kapuku, G., Huo, Y. & Bagi, Z., Aug 1 2020, In: Microcirculation. 27, 6, e12624.Research output: Contribution to journal › Article › peer-review |
Endothelial adenosine kinase deficiency ameliorates diet-induced insulin resistanceXu, J., Yang, Q., Zhang, X., Liu, Z., Cao, Y., Wang, L., Zhou, Y., Zeng, X., Ma, Q., Xu, Y., Wang, Y., Huang, L., Han, Z., Wang, T., Stepp, D., Bagi, Z., Wu, C., Hong, M. & Huo, Y., Aug 2019, In: Journal of Endocrinology. 242, 2, p. 159-172 14 p.Research output: Contribution to journal › Article › peer-review |
Adenosine kinase inhibition augments conducted vasodilation and prevents left ventricle diastolic dysfunction in heart failure with preserved ejection fractionDavila, A., Tian, Y., Czikora, I., Li, J., Su, H., Huo, Y., Patel, V., Robinson, V., Kapuku, G., Weintraub, N. & Bagi, Z., Aug 1 2019, In: Circulation: Heart Failure. 12, 8, e005762.Research output: Contribution to journal › Article › peer-review |
Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvesselsBagi, Z., Couch, Y., Broskova, Z., Perez-Balderas, F., Yeo, T., Davis, S., Fischer, R., Sibson, N. R., Davis, B. G. & Anthony, D. C., Dec 1 2019, In: Scientific reports. 9, 1, 15847.Research output: Contribution to journal › Article › peer-review |
Akt2 (protein kinase B beta) stabilizes ATP7A, a copper transporter for extracellular superoxide dismutase, in vascular smooth muscle: Novel mechanism to limit endothelial dysfunction in type 2 diabetes mellitusSudhahar, V., Okur, M. N., Bagi, Z., O'Bryan, J. P., Hay, N., Makino, A., Patel, V. S., Phillips, S. A., Stepp, D., Ushio-Fukai, M. & Fukai, T., 2018, In: Arteriosclerosis, thrombosis, and vascular biology. 38, 3, p. 529-541 13 p.Research output: Contribution to journal › Article › peer-review |
Too much TRAFfic at the crossroads of diabetes and endothelial dysfunctionBagi, Z., Jan 2018, In: American Journal of Physiology - Heart and Circulatory Physiology. 314, 1, p. H65-H67Research output: Contribution to journal › Editorial › peer-review |
Vasodilator dysfunction and oligodendrocyte dysmaturation in aging white matterBagi, Z., Brandner, D. D., Le, P., McNeal, D. W., Gong, X., Dou, H., Fulton, D. J., Beller, A., Ngyuen, T., Larson, E. B., Montine, T. J., Keene, C. D. & Back, S. A., Jan 2018, In: Annals of Neurology. 83, 1, p. 142-152 11 p.Research output: Contribution to journal › Article › peer-review |
